Rabbit anti-Human HFE Monoclonal Antibody

The antibody against HFE was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14422A

Number

Cat.No	ADA-14422A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	HFE
Target Synonyms	HH; HFE1; HLA-H; MVCD7; TFQTL2; HFE	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, A549, HT-29	Application	ELISA, WB

Cat.No

ADA-14422A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

HFE

Target Synonyms

HH; HFE1; HLA-H; MVCD7; TFQTL2; HFE

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, A549, HT-29

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201).	Target Species	Human
Immunogen Sequence	KEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE	Uniprot ID	Q30201

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201).

Target Species

Human

Immunogen Sequence

KEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE

Uniprot ID

Q30201

Background Information

Uniprot Id

Q30201
Target Species

Human
Target Name

HFE
Target Full Name

Hereditary hemochromatosis protein
Target Function

Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.
Target Involvement

Hemochromatosis 1 (HFE1); Variegate porphyria (VP); Microvascular complications of diabetes 7 (MVCD7)
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein.
Target Protein Families

MHC class I family
Target Tissue Specificity

Expressed in all tissues tested except brain.
Target Research Area

Metabolism
Target Synonyms

dJ221C16.10.1; Hemochromatosis; Hemochromatosis protein; Hereditary hemochromatosis protein; Hereditary hemochromatosis protein HLA H; HFE 1; HFE; HFE_HUMAN; HFE1; HH; High Fe; HLA H; HLA-H; HLAH; MGC:150812; MGC10379; MGC103790; MHC class I like protein HFE; MVCD7; TFQTL2
Target Background

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene.

Rabbit anti-Human HFE Monoclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human HFE Monoclonal Antibody Now

Related Products