Rabbit anti-Human Serine racemase Monoclonal Antibody

The antibody against Serine racemase was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Serine racemase (NP_068766.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14575A

Number

Cat.No	ADA-14575A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Serine racemase
Target Synonyms	ILV1; ISO1; Serine racemase	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	LNCaP, U-87 MG	Application	ELISA, WB

Cat.No

ADA-14575A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Serine racemase

Target Synonyms

ILV1; ISO1; Serine racemase

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

LNCaP, U-87 MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Serine racemase (NP_068766.1).	Target Species	Human
Immunogen Sequence	MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGI	Uniprot ID	Q9GZT4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human Serine racemase (NP_068766.1).

Target Species

Human

Immunogen Sequence

MCAQYCISFADVEKAHINIRDSIHLTPVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKPKAVVTHSSGNHGQALTYAAKLEGI

Uniprot ID

Q9GZT4

Background Information

Uniprot Id

Q9GZT4
Target Species

Human
Target Name

SRR
Target Full Name

Serine racemase
Target Function

Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
Target Protein Families

Serine/threonine dehydratase family
Target Tissue Specificity

Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
Target Research Area

Neuroscience
Target Synonyms

D serine ammonia lyase; D serine dehydratase; D-serine ammonia-lyase; D-serine dehydratase; ILV1; ISO1; L serine ammonia lyase; L serine dehydratase; L-serine ammonia-lyase; L-serine dehydratase; Serine racemase; srr; SRR_HUMAN
Target Background

Enables several functions, including L-serine ammonia-lyase activity; PDZ domain binding activity; and anion binding activity. Involved in pyruvate biosynthetic process; response to lipopolysaccharide; and serine family amino acid metabolic process. Located in cytoplasm and neuronal cell body.

Rabbit anti-Human Serine racemase Monoclonal Antibody

Specifications

Immunogen Information

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