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Rabbit anti-Human Urotensin II (UTS2) Monoclonal Antibody

The antibody against Urotensin II (UTS2) was raised in Rabbit using a synthesized peptide derived from human Urotensin II (UTS2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-15129A

The antibody against Urotensin II (UTS2) was raised in Rabbit using a synthesized peptide derived from human Urotensin II (UTS2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-15129A ClonalityMonoclonal
Host SpeciesRabbitTarget NameUrotensin II (UTS2)
Target SynonymsUII; U-II; UCN2; PRO1068; Urotensin II (UTS2)FormLiquid
Species ReactivityRatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthesized peptide derived from human Urotensin II (UTS2).Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95399
Background Information
  • Uniprot Id

    O95399

  • Target Species

    Human

  • Target Name

    UTS2

  • Target Full Name

    Urotensin-2

  • Target Function

    Highly potent vasoconstrictor.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Urotensin-2 family

  • Target Tissue Specificity

    Brain specific.

  • Target Synonyms

    PRO1068; U-II; UCN2; UII; Urotensin 2 preproprotein isoform a; Urotensin 2 preproprotein isoform b; Urotensin II; Urotensin-2; UTS2; UTS2_HUMAN; UTSII

  • Target Background

    This gene encodes a mature peptide that is an active cyclic heptapeptide absolutely conserved from lamprey to human. The active peptide acts as a vasoconstrictor and is expressed only in brain tissue. Despite the gene family name similarity, this gene is not homologous to urocortin, a member of the sauvagine/corticotropin-releasing factor/urotensin I family. Most of the proprotein is cleaved to make the mature peptide. Transcript variants encoding different preproprotein isoforms have been described for this gene.

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