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Rabbit anti-Human FLAP Monoclonal Antibody

The antibody against FLAP was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-16230A

The antibody against FLAP was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-16230A ClonalityMonoclonal
Host SpeciesRabbitTarget NameFLAP
Target SynonymsFLAPFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesA-549, THP-1, U-937ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 62-161 of human FLAP (P20292).Target SpeciesHuman
Immunogen SequenceDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIILFLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIPUniprot IDP20292
Background Information
  • Uniprot Id

    P20292

  • Target Species

    Human

  • Target Name

    ALOX5AP

  • Target Full Name

    Arachidonate 5-lipoxygenase-activating protein

  • Target Function

    Required for leukotriene biosynthesis by ALOX5 (5-lipoxygenase). Anchors ALOX5 to the membrane. Binds arachidonic acid, and could play an essential role in the transfer of arachidonic acid to ALOX5. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes.

  • Target Involvement

    Ischemic stroke (ISCHSTR)

  • Target Subcellular Location

    Nucleus membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.

  • Target Protein Families

    MAPEG family

  • Target Synonyms

    ALOX5AP; FLAP; Arachidonate 5-lipoxygenase-activating protein; MK-886-binding protein

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