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The recombinant antibody against GFAP was produced using the Recombinant Human GFAP protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG2a, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, IF, FC.
The recombinant antibody against GFAP was produced using the Recombinant Human GFAP protein as the immunogen. This antibody exists as a non-conjugated isotype Mouse IgG2a, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC, IF, FC.
$350.00
Western Blot | Positive WB detected in: MCF7 whole cell lysate,Mouse Brain tissue lysate,Rat Brain tissue lysate | All lanes: GFAP antibody at 1:1000 | Secondary | Goat polyclonal to mouse IgG at 1/50000 dilution | Predicted band size: 50 kDa | Observed band size: 55 kDa
| Cat.No | ADC-56443A | Clonality | Monoclonal |
|---|---|---|---|
| Target Name | gfap | Target Synonyms | GFAP antibody; GFAP Epsilon antibody; GFAP_HUMAN antibody; GFAPdelta antibody; GFAPepsilon antibody; Glial fibrillary acidic protein antibody; Intermediate filament protein antibody |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | Mouse IgG2a | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | Affinity-chromatography purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB, FC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human GFAP protein | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P14136 |
Uniprot Id
P14136
Target Species
Human
Target Name
GFAP
Target Full Name
Glial fibrillary acidic protein
Target Function
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Target Involvement
Alexander disease (ALXDRD)
Target Subcellular Location
Cytoplasm.
Target Protein Families
Intermediate filament family
Target Tissue Specificity
Expressed in cells lacking fibronectin.
Target Research Area
Neuroscience
Target Synonyms
ALXDRD; GFAP
Target Background
This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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