Rabbit anti-Human Desmoglein 3 Monoclonal Antibody

The antibody against Desmoglein 3 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 900-999 of human Desmoglein 3 (P32926) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-16105A

Number

Cat.No	ADA-16105A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Desmoglein 3
Target Synonyms	PVA; ABOLM; CDHF6; Desmoglein 3	Form	Liquid
Species Reactivity	Human, Mouse	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	A-431, Cal-27	Application	ELISA, WB, IF/ICC

Cat.No

ADA-16105A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Desmoglein 3

Target Synonyms

PVA; ABOLM; CDHF6; Desmoglein 3

Form

Liquid

Species Reactivity

Human, Mouse

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

A-431, Cal-27

Application

ELISA, WB, IF/ICC

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 900-999 of human Desmoglein 3 (P32926).	Target Species	Human
Immunogen Sequence	TLSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI	Uniprot ID	P32926

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 900-999 of human Desmoglein 3 (P32926).

Target Species

Human

Immunogen Sequence

TLSGSQGASALSTSGSVQPAVSIPDPLQHGNYLVTETYSASGSLVQPSTAGFDPLLTQNVIVTERVICPISSVPGNLAGPTQLRGSHTMLCTEDPCSRLI

Uniprot ID

P32926

Background Information

Uniprot Id

P32926
Target Species

Human
Target Name

DSG3
Target Full Name

Desmoglein-3
Target Function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.
Target Subcellular Location

Cell membrane; Single-pass type I membrane protein. Cell junction, desmosome.
Target Tissue Specificity

Epidermis, tongue, tonsil, esophagus and carcinomas.
Target Research Area

Signal Transduction, Cell Adhesion
Target Synonyms

130 kD pemphigus vulgaris antigen; 130 kDa pemphigus vulgaris antigen; Balding; Cadherin family member 6; CDHF 6; CDHF6; Desmoglein 3; Desmoglein 3 precursor; Desmoglein-3; Desmoglein3; DKFZp686P23184; DSG 3; DSG3; DSG3_HUMAN; Pemphigus vulgaris antigen; PVA
Target Background

This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris.

Rabbit anti-Human Desmoglein 3 Monoclonal Antibody

Specifications

Immunogen Information

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