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Rabbit anti-Human ENDOGL1 / ENGL Monoclonal Antibody

The antibody against ENDOGL1 / ENGL was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 269-368 of human ENDOGL1 / ENGL (Q9Y2C4) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13487A

The antibody against ENDOGL1 / ENGL was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 269-368 of human ENDOGL1 / ENGL (Q9Y2C4) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13487A ClonalityMonoclonal
Host SpeciesRabbitTarget NameENDOGL1 / ENGL
Target SynonymsENGL; ENGLA; ENGLB; ENGL-a; ENGL-b; ENDOGL1; ENDOGL2; ENDOGL1 / ENGLFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHL-60, HUVEC, MCF7ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 269-368 of human ENDOGL1 / ENGL (Q9Y2C4).Target SpeciesHuman
Immunogen SequenceLQDLEKLSGLVFFPHLDRTSDIRNICSVDTCKLLDFQEFTLYLSTRKIEGARSVLRLEKIMENLKNAEIEPDDYFMSRYEKKLEELKAKEQSGTQIRKPSUniprot IDQ9Y2C4
Background Information
  • Uniprot Id

    Q9Y2C4

  • Target Species

    Human

  • Target Name

    EXOG

  • Target Full Name

    Nuclease EXOG, mitochondrial

  • Target Function

    Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5'-3' exonuclease activity.

  • Target Subcellular Location

    Mitochondrion inner membrane.

  • Target Protein Families

    DNA/RNA non-specific endonuclease family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    Endo G like 1; Endo G-like 1; Endo/exonuclease (5'-3'); endonuclease G like; ENDOGL 1; ENDOGL1; ENDOGL2; Endonuclease G like 1; Endonuclease G like 2; Endonuclease G-like 1; ENGL a; ENGL; ENGL B; ENGLA; ENGLB; Exog; EXOG_HUMAN; MGC125944; MGC125945; mitochondrial; Nuclease EXOG; Nuclease EXOG mitochondrial

  • Target Background

    This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18.

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