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Rabbit anti-Human GALT Monoclonal Antibody

The antibody against GALT was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GALT (P07902) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-13468A

The antibody against GALT was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human GALT (P07902) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-13468A ClonalityMonoclonal
Host SpeciesRabbitTarget NameGALT
Target SynonymsGALTFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, HepG2ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 1-100 of human GALT (P07902).Target SpeciesHuman
Immunogen SequenceMSRSGTDPQQRQQASEADAAAATFRANDHQHIRYNPLQDEWVLVSAHRMKRPWQGQVEPQLLKTVPRHDPLNPLCPGAIRANGEVNPQYDSTFLFDNDFPUniprot IDP07902
Background Information
  • Uniprot Id

    P07902

  • Target Species

    Human

  • Target Name

    GALT

  • Target Full Name

    Galactose-1-phosphate uridylyltransferase

  • Target Function

    Plays an important role in galactose metabolism.

  • Target Involvement

    Galactosemia (GALCT)

  • Target Protein Families

    Galactose-1-phosphate uridylyltransferase type 1 family

  • Target Research Area

    Metabolism

  • Target Synonyms

    Gal 1 P uridylyltransferase; Gal-1-P uridylyltransferase; Galactose 1 phosphate uridyl transferase; Galactose 1 phosphate uridylyltransferase; Galactose-1-phosphate uridylyltransferase; GALT; GALT_HUMAN; UDP glucose hexose 1 phosphate uridylyltransferase; UDP-glucose--hexose-1-phosphate uridylyltransferase

  • Target Background

    Galactose-1-phosphate uridyl transferase (GALT) catalyzes the second step of the Leloir pathway of galactose metabolism, namely the conversion of UDP-glucose + galactose-1-phosphate to glucose-1-phosphate + UDP-galactose. The absence of this enzyme results in classic galactosemia in humans and can be fatal in the newborn period if lactose is not removed from the diet. The pathophysiology of galactosemia has not been clearly defined. Two transcript variants encoding different isoforms have been found for this gene.

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