Rabbit anti-Human Kallistatin (SERPINA4) Monoclonal Antibody

The antibody against Kallistatin (SERPINA4) was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human Kallistatin (SERPINA4) (NP_006206.2) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14777A

Number

Cat.No	ADA-14777A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	Kallistatin (SERPINA4)
Target Synonyms	KAL; KST; PI4; KLST; PI-4; kallistatin; Kallistatin (SERPINA4)	Form	Liquid
Species Reactivity	Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat plasma	Application	ELISA, WB

Cat.No

ADA-14777A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

Kallistatin (SERPINA4)

Target Synonyms

KAL; KST; PI4; KLST; PI-4; kallistatin; Kallistatin (SERPINA4)

Form

Liquid

Species Reactivity

Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat plasma

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Kallistatin (SERPINA4) (NP_006206.2).	Target Species	Human
Immunogen Sequence	MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQ	Uniprot ID	P29622

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Kallistatin (SERPINA4) (NP_006206.2).

Target Species

Human

Immunogen Sequence

MHLIDYLLLLLVGLLALSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQ

Uniprot ID

P29622

Background Information

Uniprot Id

P29622
Target Species

Human
Target Name

SERPINA4
Target Full Name

Kallistatin
Target Function

Inhibits human amidolytic and kininogenase activities of tissue kallikrein. Inhibition is achieved by formation of an equimolar, heat- and SDS-stable complex between the inhibitor and the enzyme, and generation of a small C-terminal fragment of the inhibitor due to cleavage at the reactive site by tissue kallikrein.
Target Subcellular Location

Secreted.
Target Protein Families

Serpin family
Target Tissue Specificity

Expressed by the liver and secreted in plasma.
Target Synonyms

KAIN_HUMAN; KAL; Kallikrein binding protein; Kallikrein inhibitor; Kallistatin; KBP; KLST ; KST; MGC108582; Peptidase inhibitor 4; PI-4; PI4; Protease inhibitor 4 (kallistatin); Protease inhibitor 4; Serine (or cysteine) proteinase inhibitor; clade A (alpha 1 antiproteinase; antitrypsin); member 4; Serpin A4; Serpin peptidase inhibitor clade A member 4; Serpin peptidase inhibitor; clade A (alpha 1 antiproteinase; antitrypsin); member 4; SERPINA4; Tissue kallistatin inhibitor
Target Background

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity. Located in extracellular exosome. Biomarker of diabetic retinopathy.

Rabbit anti-Human Kallistatin (SERPINA4) Monoclonal Antibody

Specifications

Immunogen Information

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