Rabbit anti-Human MUTA Monoclonal Antibody

The antibody against MUTA was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 500-600 of human MUTA (P22033) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-14400A

Number

Cat.No	ADA-14400A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	MUTA
Target Synonyms	MCM; MUT; MUTA	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HeLa, HepG2	Application	ELISA, WB, IF/ICC, IHC-P

Cat.No

ADA-14400A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

MUTA

Target Synonyms

MCM; MUT; MUTA

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HeLa, HepG2

Application

ELISA, WB, IF/ICC, IHC-P

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 500-600 of human MUTA (P22033).	Target Species	Human
Immunogen Sequence	VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSA	Uniprot ID	P22033

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 500-600 of human MUTA (P22033).

Target Species

Human

Immunogen Sequence

VEVLAIDNTSVRNRQIEKLKKIKSSRDQALAERCLAALTECAASGDGNILALAVDASRARCTVGEITDALKKVFGEHKANDRMVSGAYRQEFGESKEITSA

Uniprot ID

P22033

Background Information

Uniprot Id

P22033
Target Species

Human
Target Name

MMUT
Target Full Name

Methylmalonyl-CoA mutase, mitochondrial
Target Function

Catalyzes the reversible isomerization of methylmalonyl-CoA (MMCoA) (generated from branched-chain amino acid metabolism and degradation of dietary odd chain fatty acids and cholesterol) to succinyl-CoA (3-carboxypropionyl-CoA), a key intermediate of the tricarboxylic acid cycle.
Target Involvement

Methylmalonic aciduria type mut (MMAM)
Target Subcellular Location

Mitochondrion matrix. Mitochondrion. Cytoplasm.
Target Protein Families

Methylmalonyl-CoA mutase family
Target Research Area

Signal Transduction
Target Synonyms

MCM; Methylmalonyl CoA isomerase ; Methylmalonyl CoA mutase mitochondrial; Methylmalonyl Coenzyme A mutase; Methylmalonyl-CoA isomerase; Methylmalonyl-CoA mutase; mitochondrial; Mut; MUTA_HUMAN
Target Background

This gene encodes the mitochondrial enzyme methylmalonyl Coenzyme A mutase. In humans, the product of this gene is a vitamin B12-dependent enzyme which catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA, while in other species this enzyme may have different functions. Mutations in this gene may lead to various types of methylmalonic aciduria.

Rabbit anti-Human MUTA Monoclonal Antibody

Specifications

Immunogen Information

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