Rabbit anti-Human ODC1 Monoclonal Antibody

The antibody against ODC1 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-14399A

Number

Cat.No	ADA-14399A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	ODC1
Target Synonyms	ODC; BABS; NEDBA; NEDBIA; ODC1	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	U-937	Application	ELISA, WB

Cat.No

ADA-14399A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

ODC1

Target Synonyms

ODC; BABS; NEDBA; NEDBIA; ODC1

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

U-937

Application

ELISA, WB

Immunogen Description	A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).	Target Species	Human
Immunogen Sequence	MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQS	Uniprot ID	P11926

Immunogen Description

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ODC1 (P11926).

Target Species

Human

Immunogen Sequence

MNNFGNEEFDCHFLDEGFTAKDILDQKINEVSSSDDKDAFYVADLGDILKKHLRWLKALPRVTPFYAVKCNDSKAIVKTLAATGTGFDCASKTEIQLVQS

Uniprot ID

P11926

Background Information

Uniprot Id

P11926
Target Species

Human
Target Name

ODC1
Target Full Name

Ornithine decarboxylase
Target Function

Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.
Target Protein Families

Orn/Lys/Arg decarboxylase class-II family
Target Research Area

Signal Transduction
Target Synonyms

DCOR_HUMAN; Dodc1; Odc 1; ODC; Odc1; ODC2; Ornithine decarboxylase 1; Ornithine decarboxylase 2; Ornithine decarboxylase; Ornithine decarboxylase structural 1; RNODC
Target Background

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified.

Rabbit anti-Human ODC1 Monoclonal Antibody

Specifications

Immunogen Information

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