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Rabbit anti-Human Talin 2 Monoclonal Antibody

The antibody against Talin 2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human Talin 2 (Q9Y4G6) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

ADA-16241A

The antibody against Talin 2 was raised in Rabbit using a synthetic peptide corresponding to a sequence within amino acids 350-450 of human Talin 2 (Q9Y4G6) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.

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Specifications


Cat.No ADA-16241A ClonalityMonoclonal
Host SpeciesRabbitTarget NameTalin 2
Target SynonymsILWEQ; TLN2; Talin-2; Talin 2FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, 0.05% BSA, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesHeLa, NIH/3T3, Mouse testis, Rat testisApplicationELISA, WB, IF/ICC, IHC-P

Immunogen Information


Immunogen DescriptionA synthetic peptide corresponding to a sequence within amino acids 350-450 of human Talin 2 (Q9Y4G6).Target SpeciesHuman
Immunogen SequenceVLQEWPLTTVKRWAASPKSFTLDFGEYQESYYSVQTTEGEQISQLIAGYIDIILKKKQSKDRFGLEGDEESTMLEESVSPKKSTILQQQFNRTGKAEHGSVUniprot IDQ9Y4G6
Background Information
  • Uniprot Id

    Q9Y4G6

  • Target Species

    Human

  • Target Name

    TLN2

  • Target Full Name

    Talin-2

  • Target Function

    As a major component of focal adhesion plaques that links integrin to the actin cytoskeleton, may play an important role in cell adhesion. Recruits PIP5K1C to focal adhesion plaques and strongly activates its kinase activity.

  • Target Subcellular Location

    Cytoplasm. Cell junction, focal adhesion. Cell junction, synapse. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton.

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    DKFZp451B1011; DKFZp686I0976; DKFZp686K0979; ILWEQ; KIAA0320; Talin-2; talin2; TLN 2; TLN2; TLN2_HUMAN

  • Target Background

    This gene encodes a protein related to talin 1, a cytoskeletal protein that plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. This protein has a different pattern of expression compared to talin 1 but, like talin 1, is thought to associate with unique transmembrane receptors to form novel linkages between extracellular matrices and the actin cytoskeleton.

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