Rabbit anti-Human HTN3 Polyclonal Antibody, HRP conjugated

Uniprot Id

P15516

Target Species

Human

Target Name

HTN3

Target Full Name

Histatin-3

Target Function

Histatins are salivary proteins that are considered to be major precursors of the protective proteinaceous structure on tooth surfaces (enamel pellicle). In addition, histatins exhibit antibacterial and antifungal activities. His3-(20-43)-peptide (histatin-5) is especially effective against C.albicans and C.neoformans, and inhibits Lys-gingipain and Arg-gingipain (rgpB) from P.gingivalis. In addition, His3-(20-43)-peptide is a potent inhibitor of metalloproteinases MMP2 and MMP9.

Target Subcellular Location

Secreted. Note=Secreted by serous acinar and demilune cells.

Target Protein Families

Histatin/statherin family

Target Synonyms

HTN3; HIS2; Histatin-3; Basic histidine-rich protein; Hst; Histidine-rich protein 3; PB) [Cleaved into: Histatin-3; His3-(20-44)-peptide; His3 20/44; His3-(1-25)-peptide; His3 1/25; Histatin-3 1/25; Histatin-6); His3-(20-43)-peptide; His3 20/43; His3-(1-24)-peptide; His3 1/24; Histatin-3 1/24; Histatin-5); His3-(20-32)-peptide; His3 20/32; His3-(1-13)-peptide; His3 1/13; Histatin-3 1/13); His3-(20-31)-peptide; His3 20/31; His3-(1-12)-peptide; His3 1/12; Histatin-3 1/12); His3-(20-30)-peptide; His3 20/30; His3-(1-11)-peptide; His3 1/11; Histatin-3 1/11); His3-(24-32)-peptide; His3 24/32; His3-(5-13)-peptide; His3 5/13; Histatin-3 5/13); His3-(24-31)-peptide; His3 24/31; His3-(5-12)-peptide; His3 5/12; Histatin-11; Histatin-3 5/12); His3-(24-30)-peptide; His3 24/30; His3-(5-11)-peptide; His3 5/11; Histatin-12; Histatin-3 5/11); His3-(25-32)-peptide; His3 25/32; His3-(6-13)-peptide; His3 6/13; Histatin-3 6/13); His3-(25-30)-peptide; His3 25/30; His3-(6-11)-peptide; His3 6/11; Histatin-3 6/11); His3-(26-32)-peptide; His3 26/32; His3-(7-13)-peptide; His3 7/13; Histatin-3 7/13); His3-(26-31)-peptide; His3 26/31; His3-(7-12)-peptide; His3 7/12; Histatin-3 7/12); His3-(26-30)-peptide; His3 26/30; His3-(7-11)-peptide; His3 7/11; Histatin-3 7/11); His3-(31-51)-peptide; His3 31/51; His3-(12-32)-peptide; His3 12/32; Histatin-3 12/32; Histatin-4); His3-(31-44)-peptide; His3 31/44; His3-(12-25)-peptide; His3 12/25; Histatin-3 12/25; Histatin-9); His3-(31-43)-peptide; His3 31/43; His3-(12-24)-peptide; His3 12/24; Histatin-3 12/24; Histatin-7); His3-(32-44)-peptide; His3 32/44; His3-(13-25)-peptide; His3 13/25; Histatin-10; Histatin-3 13/25); His3-(32-43)-peptide; His3 32-43; His3-(13-24)-peptide; His3 13/24; Histatin-3 13/24; Histatin-8); His3-(33-44)-peptide; His3 33/44; His3-(14-25)-peptide; His3 14/25; Histatin-3 14/25); His3-(33-43)-peptide; His3 33/43; His3-(14-24)-peptide; His3 14/24; Histatin-3 14/24); His3-(34-44)-peptide; His3 34/44; His3-(15-25)-peptide; His3 15/25; Histatin-3 15/25); His3-(34-43)-peptide; His3 34/43; His3-(15-24)-peptide; His3 15/24; Histatin-3 15/24); His3-(45-51)-peptide; His3 45/51; His3-(26-32)-peptide; His3 26/32; Histatin-3 26/32); His3-(47-51)-peptide; His3 47/51; His3-(28-32)-peptide; His3 28/32; Histatin-3 28/32); His3-(48-51)-peptide; His3 48/51; His3-(29-32)-peptide; His3 29/32; Histatin-3 29/32)]