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The antibody against OXT was raised in rabbit using the Recombinant Human Oxytocin-neurophysin 1 protein (27-123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against OXT was raised in rabbit using the Recombinant Human Oxytocin-neurophysin 1 protein (27-123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human liver tissue using OXT Antibody at dilution of 1:1002
| Cat.No | ADC-12545A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | OXT |
| Target Synonyms | OXT antibody; OT antibody; Oxytocin-neurophysin 1 antibody; OT-NPI) [Cleaved into: Oxytocin antibody; Ocytocin); Neurophysin 1] antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Oxytocin-neurophysin 1 protein (27-123AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P01178 |
Uniprot Id
P01178
Target Species
Human
Target Name
OXT
Target Full Name
Oxytocin-neurophysin 1
Target Function
Neurophysin 1 specifically binds oxytocin.; Oxytocin causes contraction of the smooth muscle of the uterus and of the mammary gland. Acts by binding to oxytocin receptor (OXTR).
Target Subcellular Location
Secreted.
Target Protein Families
Vasopressin/oxytocin family
Target Research Area
others
Target Synonyms
OXT; OT; Oxytocin-neurophysin 1; OT-NPI) [Cleaved into: Oxytocin; Ocytocin); Neurophysin 1]
Target Background
This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
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