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Rabbit anti-Human HESX1 Polyclonal Antibody, FITC conjugated

The antibody against HESX1 was raised in rabbit using the Recombinant Human Homeobox expressed in ES cells 1 protein (1-185AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-18261A

The antibody against HESX1 was raised in rabbit using the Recombinant Human Homeobox expressed in ES cells 1 protein (1-185AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-18261A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHESX1
Target SynonymsHESX1 antibody; HANF antibody; Homeobox expressed in ES cells 1 antibody; Homeobox protein ANF antibody; hAnf antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateFITC conjugatedStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Homeobox expressed in ES cells 1 protein (1-185AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBX0
Background Information
  • Uniprot Id

    Q9UBX0

  • Target Species

    Human

  • Target Name

    HESX1

  • Target Full Name

    Homeobox expressed in ES cells 1

  • Target Function

    Required for the normal development of the forebrain, eyes and other anterior structures such as the olfactory placodes and pituitary gland. Possible transcriptional repressor. Binds to the palindromic PIII sequence, 5'-AGCTTGAGTCTAATTGAATTAACTGTAC-3'. HESX1 and PROP1 bind as heterodimers on this palindromic site, and, in vitro, HESX1 can antagonize PROP1 activation.

  • Target Involvement

    Septooptic dysplasia (SOD); Growth hormone deficiency with pituitary anomalies (GHDPA); Pituitary hormone deficiency, combined, 5 (CPHD5)

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    ANF homeobox family

  • Target Synonyms

    HESX1; HANF; Homeobox expressed in ES cells 1; Homeobox protein ANF; hAnf

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