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Rabbit anti-Human DYNC1LI1 Polyclonal Antibody

The antibody against DYNC1LI1 was raised in rabbit using the Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 protein (167-233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

ADC-01934A

The antibody against DYNC1LI1 was raised in rabbit using the Recombinant Human Cytoplasmic dynein 1 light intermediate chain 1 protein (167-233AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-01934A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDYNC1LI1
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cytoplasmic dynein 1 light intermediate chain 1 protein (167-233AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y6G9
Background Information
  • Uniprot Id

    Q9Y6G9

  • Target Species

    Human

  • Target Name

    DYNC1LI1

  • Target Full Name

    Cytoplasmic dynein 1 light intermediate chain 1

  • Target Function

    Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress through the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores.

  • Target Subcellular Location

    Cytoplasm. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle pole.

  • Target Protein Families

    Dynein light intermediate chain family

  • Target Synonyms

    Cytoplasmic dynein 1 light intermediate chain 1; cytosolic; DC1L1_HUMAN; DLC-A; DNCLI1; dync1li1; Dynein cytoplasmic 1 light intermediate chain 1; Dynein cytoplasmic light intermediate polypeptide 1; Dynein light chain A; Dynein light intermediate chain 1; Dynein light intermediate chain 1 cytosolic; FLJ10219; LIC1

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