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Rabbit anti-Human HERC3 Polyclonal Antibody, Biotin conjugated

The antibody against HERC3 was raised in rabbit using the Recombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-20275A

The antibody against HERC3 was raised in rabbit using the Recombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-20275A ClonalityPolyclonal
Host SpeciesRabbitTarget NameHERC3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateBiotin conjugated
ApplicationELISAStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Probable E3 ubiquitin-protein ligase HERC3 protein (1-200AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ15034
Background Information
  • Uniprot Id

    Q15034

  • Target Species

    Human

  • Target Name

    HERC3

  • Target Full Name

    Probable E3 ubiquitin-protein ligase HERC3

  • Target Function

    E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.

  • Target Subcellular Location

    Cytoplasm. Cytoplasmic vesicle. Note=Also found in vesicular-like structures.

  • Target Synonyms

    HERC3; KIAA0032Probable E3 ubiquitin-protein ligase HERC3; EC 2.3.2.26; HECT domain and RCC1-like domain-containing protein 3; HECT-type E3 ubiquitin transferase HERC3

  • Target Background

    This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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