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The antibody against CLIC2 was raised in rabbit using the Recombinant Human Chloride intracellular channel protein 2 protein (53-247AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CLIC2 was raised in rabbit using the Recombinant Human Chloride intracellular channel protein 2 protein (53-247AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CLIC2 Antibody at dilution of 1:100
Immunofluorescent analysis of HepG2 cells using CLIC2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-22166A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLIC2 |
| Target Synonyms | CLIC2; Chloride intracellular channel protein 2; XAP121 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Chloride intracellular channel protein 2 protein (53-247AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O15247 |
Uniprot Id
O15247
Target Species
Human
Target Name
CLIC2
Target Full Name
Chloride intracellular channel protein 2
Target Function
Can insert into membranes and form chloride ion channels. Channel activity depends on the pH. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Modulates the activity of RYR2 and inhibits calcium influx.
Target Involvement
Mental retardation, X-linked, syndromic, 32 (MRXS32)
Target Subcellular Location
Cytoplasm. Membrane; Single-pass membrane protein. Note=Exists both as soluble cytoplasmic protein and as membrane protein with probably a single transmembrane domain.
Target Protein Families
Chloride channel CLIC family
Target Tissue Specificity
Expressed in adult and fetal brain, heart, skeletal muscle, liver, lung, and spleen. Detected in adult stomach and testis. Expressed in fetal thymus and kidney.
Target Synonyms
CLIC2; Chloride intracellular channel protein 2; XAP121
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