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The antibody against USP45 was raised in rabbit using the Recombinant Human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against USP45 was raised in rabbit using the Recombinant Human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using USP45 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using USP45 Antibody at dilution of 1:1002
| Cat.No | ADC-32628A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | USP45 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Ubiquitin carboxyl-terminal hydrolase 45 protein (1-240AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q70EL2 |
Uniprot Id
Q70EL2
Target Species
Human
Target Name
USP45
Target Full Name
Ubiquitin carboxyl-terminal hydrolase 45
Target Function
Catalyzes the deubiquitination of SPDL1. Plays a role in the repair of UV-induced DNA damage via deubiquitination of ERCC1, promoting its recruitment to DNA damage sites. May be involved in the maintenance of photoreceptor function. May play a role in normal retinal development. Plays a role in cell migration.
Target Subcellular Location
Photoreceptor inner segment. Cytoplasm. Nucleus.
Target Protein Families
Peptidase C19 family
Target Tissue Specificity
Widely expressed. High expression is detected in the cerebellum. In the eye, it is expressed at high levels in the optic nerve, sclera and retina, with relatively low levels in the choroid, lens and retinal pigment epithelium.
Target Synonyms
USP45; Ubiquitin carboxyl-terminal hydrolase 45; EC 3.4.19.12; Deubiquitinating enzyme 45; Ubiquitin thioesterase 45; Ubiquitin-specific-processing protease 45
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