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The antibody against SPIC was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Spi-C. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
The antibody against SPIC was raised in rabbit using the Synthesized peptide derived from the Internal region of Human Spi-C. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IF, ELISA.
$167.00
Western Blot analysis of HeLa cells using Spi-C Polyclonal Antibody
| Cat.No | ADC-37583A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | SPIC |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human Spi-C. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N5J4 |
Uniprot Id
Q8N5J4
Target Species
Human
Target Name
SPIC
Target Full Name
Transcription factor Spi-C
Target Function
Controls the development of red pulp macrophages required for red blood cells recycling and iron homeostasis. Transcription factor that binds to the PU-box, a purine-rich DNA sequence (5'-GAGGA[AT]-3') that can act as a lymphoid-specific enhancer. Regulates VCAM1 gene expression.
Target Subcellular Location
Nucleus.
Target Protein Families
ETS family
Target Tissue Specificity
Preferentially detected in fetal and adult spleen, lymph nodes and at lower levels in bone marrow and fetal liver.
Target Synonyms
AU019198; C76795; MGC40611; MGC80555; Prf; Pu.1 related factor; Spi C; Spi C transcription factor; Spi-C transcription factor (Spi-1/PU.1 related); spiC; SPIC_HUMAN; Transcription factor Spi-C
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