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The antibody against NUDC was raised in rabbit using the Peptide sequence around phosphorylation site of serine 326 (D-F-S(p)-K-A) derived from Human NudC. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB, IHC.
The antibody against NUDC was raised in rabbit using the Peptide sequence around phosphorylation site of serine 326 (D-F-S(p)-K-A) derived from Human NudC. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from rat brain cells, using NudC (Phospho-Ser326) antibody. The lane on the right is treated with the synthesized peptide.
Western blot analysis of extracts from HepG2 cells (Lane 2), using NudC (Phospho-Ser326) Antibody. The lane on the left is treated with synthesized peptide.2
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NudC (Phospho-Ser326) antibody. The picture on the right is treated with the synthesized peptide.3
| Cat.No | ADC-40569A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | NUDC |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Peptide sequence around phosphorylation site of serine 326 (D-F-S(p)-K-A) derived from Human NudC. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9Y266 |
Uniprot Id
Q9Y266
Target Species
Human
Target Name
NUDC
Target Full Name
Nuclear migration protein nudC
Target Function
Plays a role in neurogenesis and neuronal migration. Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
Target Subcellular Location
Cytoplasm, cytoskeleton. Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody.
Target Protein Families
NudC family
Target Tissue Specificity
Ubiquitous. Highly expressed in fetal liver, kidney, lung and brain. Highly expressed in adult pancreas, kidney, skeletal muscle, liver, lung, placenta, prostate, brain and heart.
Target Synonyms
HNUDC; MNUDC; NPD011; NUDC
Target Background
This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2.
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