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The antibody against CDC40 was raised in rabbit using the Synthesized peptide derived from internal of Human CDC40. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CDC40 was raised in rabbit using the Synthesized peptide derived from internal of Human CDC40. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from K562 cells, HUVEC cells and COLO cells, using CDC40 antibody.
| Cat.No | ADC-41021A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CDC40 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CDC40. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60508 |
Uniprot Id
O60508
Target Species
Human
Target Name
CDC40
Target Full Name
Pre-mRNA-processing factor 17
Target Function
Required for pre-mRNA splicing as component of the activated spliceosome.
Target Subcellular Location
Nucleus. Nucleus speckle.
Target Synonyms
Cdc40; Cell division cycle 40; Cell division cycle 40 homolog; EH binding protein 3; EH-binding protein 3; Ehb3; hPRP17; Pre mRNA processing factor 17; Pre mRNA splicing factor 17; Pre-mRNA-processing factor 17; PRP17; PRP17 homolog; PRP17_HUMAN; PRPF17
Target Background
Pre-mRNA splicing occurs in two sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp17 protein, which functions in two different cellular processes: pre-mRNA splicing and cell cycle progression. It suggests that this protein may play a role in cell cycle progression.
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