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The antibody against HES5 was raised in rabbit using the Recombinant Human Transcription factor HES-5 protein (1-166AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against HES5 was raised in rabbit using the Recombinant Human Transcription factor HES-5 protein (1-166AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-04854A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | HES5 |
| Target Synonyms | 5 antibody; HES 5 antibody; hes family bHLH transcription factor 5 antibody; Hes5 antibody; HES5 protein antibody; HES5_HUMAN antibody; MGI:104876 antibody; Transcription factor HES-5 antibody, bHLHb38 antibody; Class B basic helix-loop-helix protein 38 antibody; Hairy and enhancer of split 5 antibody; Hairy/Enhancer of spli, Drosophila, homolog of | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | HRP conjugated | Application | ELISA |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Transcription factor HES-5 protein (1-166AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5TA89 |
Uniprot Id
Q5TA89
Target Species
Human
Target Name
HES5
Target Full Name
Transcription factor HES-5
Target Function
Transcriptional repressor of genes that require a bHLH protein for their transcription. Plays an important role as neurogenesis negative regulator.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Expressed in fetal heart and brain tumors.
Target Synonyms
bHLHb38; Class B basic helix-loop-helix protein 38; Hairy and enhancer of split 5; Hairy/Enhancer of spli, Drosophila, homolog of, 5; HES 5; hes family bHLH transcription factor 5; Hes5; HES5 protein; HES5_HUMAN; MGI:104876; Transcription factor HES-5
Target Background
This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer.
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