Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against DGKH was raised in rabbit using the Synthesized peptide derived from internal of Human DGKH. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC, IF.
The antibody against DGKH was raised in rabbit using the Synthesized peptide derived from internal of Human DGKH. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, IHC, IF.
$297.00
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using DGKH antibody.
Immunofluorescence analysis of HeLa cells, using DGKH antibody.2
| Cat.No | ADC-41903A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DGKH |
| Target Synonyms | DGKHDiacylglycerol kinase eta antibody; DAG kinase eta antibody; EC 2.7.1.107 antibody; Diglyceride kinase eta antibody; DGK-eta antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human DGKH. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86XP1 |
Uniprot Id
Q86XP1
Target Species
Human
Target Name
DGKH
Target Full Name
Diacylglycerol kinase eta
Target Function
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). Plays a key role in promoting cell growth. Activates the Ras/B-Raf/C-Raf/MEK/ERK signaling pathway induced by EGF. Regulates the recruitment of RAF1 and BRAF from cytoplasm to membranes and their heterodimerization.
Target Subcellular Location
Cytoplasm. Cell membrane. Note=Translocated from the cytoplasm to endosomes in response to stress stimuli (PubMed:12810723). Isoform 2 is rapidly relocated back to the cytoplasm upon removal of stress stimuli, whereas isoform 1 exhibits sustained endosomal association (PubMed:12810723). Translocates from the cytoplasm to the cell membrane in the presence of active GTP-bound form of HRAS (PubMed:19710016).
Target Protein Families
Eukaryotic diacylglycerol kinase family
Target Tissue Specificity
[Isoform 1]: Expressed only in testis, kidney and colon.; [Isoform 2]: Ubiquitously expressed.
Target Synonyms
DGKHDiacylglycerol kinase eta; DAG kinase eta; EC 2.7.1.107; Diglyceride kinase eta; DGK-eta
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
