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The antibody against CLDN5 was raised in rabbit using a synthesized peptide derived from Human Claudin 5 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CLDN5 was raised in rabbit using a synthesized peptide derived from Human Claudin 5 as the immunogen. This antibody exists as a polyclonal antibody to the immunogen, Affinity-chromatography purified. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis on A549 cell lysate using Claudin 5 Antibody
| Cat.No | ADC-42897A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLDN5 |
| Target Synonyms | CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline |
| Purification Method | Affinity-chromatography purified | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | A synthesized peptide derived from Human Claudin 5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O00501 |
Uniprot Id
O00501
Target Species
Human
Target Name
CLDN5
Target Full Name
Claudin-5
Target Function
Plays a major role in tight junction-specific obliteration of the intercellular space.
Target Subcellular Location
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Target Protein Families
Claudin family
Target Synonyms
CLDN5; AWAL; TMVCF; Claudin-5; Transmembrane protein deleted in VCFS; TMDVCF
Target Background
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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