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The antibody against PACS2 was raised in rabbit using the Recombinant Human Phosphofurin acidic cluster sorting protein 2 protein (268-465AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against PACS2 was raised in rabbit using the Recombinant Human Phosphofurin acidic cluster sorting protein 2 protein (268-465AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-05929A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | PACS2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | HRP conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phosphofurin acidic cluster sorting protein 2 protein (268-465AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86VP3 |
Uniprot Id
Q86VP3
Target Species
Human
Target Name
PACS2
Target Full Name
Phosphofurin acidic cluster sorting protein 2
Target Function
Multifunctional sorting protein that controls the endoplasmic reticulum (ER)-mitochondria communication, including the apposition of mitochondria with the ER and ER homeostasis. In addition, in response to apoptotic inducer, translocates BIB to mitochondria, which initiates a sequence of events including the formation of mitochondrial truncated BID, the release of cytochrome c, the activation of caspase-3 thereby causing cell death. May also be involved in ion channel trafficking, directing acidic cluster-containing ion channels to distinct subcellular compartments.
Target Subcellular Location
Endoplasmic reticulum. Mitochondrion.
Target Protein Families
PACS family
Target Tissue Specificity
Broadly expressed, with greatest levels in skeletal muscle followed by heart, brain, pancreas and testis.
Target Synonyms
6720425G15Rik; AW208651; AW489976; E230011J22; FLJ25488; KIAA0602; mKIAA0602; PACS 2; PACS-2; PACS1 like protein; PACS1-like protein; PACS1L; PACS2; PACS2_HUMAN; Phosphofurin acidic cluster sorting protein 1 like; Phosphofurin acidic cluster sorting protein 2
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