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The antibody against GPR137B was raised in rabbit using the Human GPR137B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against GPR137B was raised in rabbit using the Human GPR137B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-48424A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | GPR137B |
| Target Synonyms | GPR137B; TM7SF1; Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Human GPR137B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O60478 |
Uniprot Id
O60478
Target Species
Human
Target Name
GPR137B
Target Full Name
Integral membrane protein GPR137B
Target Function
Lysosomal integral membrane protein that regulates the localization and activity of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Interacts with Rag GTPases and increases the lysosomial localization and activity of Rag GTPases and thereby regulates mTORC1 translocation and activity in lysosome. Involved in the regulation of lysosomal morphology and autophagy.; Acts also as a negative regulator of osteoclast activity. Involved in interleukin-4-induced M2 macrophage polarization.
Target Subcellular Location
Lysosome membrane; Multi-pass membrane protein.
Target Protein Families
GPR137 family
Target Tissue Specificity
Expressed in kidney, heart, brain and placenta.
Target Synonyms
GPR137B; TM7SF1; Integral membrane protein GPR137B; Transmembrane 7 superfamily member 1 protein
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