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The antibody against FREM2 was raised in rabbit using the Recombinant Human FRAS1-related extracellular matrix protein 2 protein (1986-2127AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against FREM2 was raised in rabbit using the Recombinant Human FRAS1-related extracellular matrix protein 2 protein (1986-2127AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-06585A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | FREM2 |
| Target Synonyms | DKFZp781I048 antibody; ECM3 homolog antibody; FRAS1-related extracellular matrix protein 2 antibody; FREM 2 antibody; Frem2 antibody; FREM2_HUMAN antibody; KIAA1074 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human FRAS1-related extracellular matrix protein 2 protein (1986-2127AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5SZK8 |
Uniprot Id
Q5SZK8
Target Species
Human
Target Name
FREM2
Target Full Name
FRAS1-related extracellular matrix protein 2
Target Function
Extracellular matrix protein required for maintenance of the integrity of the skin epithelium and for maintenance of renal epithelia. Required for epidermal adhesion. Involved in the development of eyelids and the anterior segment of the eyeballs.
Target Involvement
Fraser syndrome 2 (FRASRS2)
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein.
Target Protein Families
FRAS1 family
Target Synonyms
DKFZp781I048; ECM3 homolog; FRAS1-related extracellular matrix protein 2; FREM 2; Frem2; FREM2_HUMAN; KIAA1074
Target Background
This gene encodes an integral membrane protein containing numerous CSPG (chondroitin sulfate proteoglycan element) repeats and Calx-beta domains. The encoded protein localizes to the basement membrane, forming a ternary complex that plays a role in epidermal-dermal interactions. This protein is important for the integrity of skin and renal epithelia. Mutations in this gene are associated with Fraser syndrome.
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