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Rabbit anti-Human AFF2 Polyclonal Antibody

The antibody against AFF2 was raised in rabbit using the Recombinant Human AF4/FMR2 family member 2 protein (575-705AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-06968A

The antibody against AFF2 was raised in rabbit using the Recombinant Human AF4/FMR2 family member 2 protein (575-705AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-06968A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAFF2
Target SynonymsAF4/FMR2 family member 2 antibody; AF4/FMR2 familyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human AF4/FMR2 family member 2 protein (575-705AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP51816
Background Information
  • Uniprot Id

    P51816

  • Target Species

    Human

  • Target Name

    AFF2

  • Target Full Name

    AF4/FMR2 family member 2

  • Target Function

    RNA-binding protein. Might be involved in alternative splicing regulation through an interaction with G-quartet RNA structure.

  • Target Involvement

    Mental retardation, X-linked, associated with fragile site FRAXE (MRFRAXE)

  • Target Subcellular Location

    Nucleus speckle. Note=When splicing is inhibited, accumulates in enlarged speckles.

  • Target Protein Families

    AF4 family

  • Target Tissue Specificity

    Brain (most abundant in hippocampus and amygdala), placenta and lung.

  • Target Synonyms

    AF4/FMR2 family member 2; AF4/FMR2 family, member 2; AFF2; AFF2_HUMAN; FMR2; FMR2P; Fragile X E mental retardation syndrome protein; fragile X mental retardation 2; Fragile X mental retardation 2 protein; fragile X mental retardation gene associated with FRAXE; FRAXE; mild or borderline mental retardation; MRX2; OTTHUMP00000024204; OX19; Protein FMR-2; Protein Ox19

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