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Rabbit anti-Bacillus subtilis (strain 168) ptsH Polyclonal Antibody, HRP conjugated

The antibody against ptsH was raised in rabbit using the Recombinant Bacillus subtilis Phosphocarrier protein HPr protein (2-88AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-12090A

The antibody against ptsH was raised in rabbit using the Recombinant Bacillus subtilis Phosphocarrier protein HPr protein (2-88AA) as the immunogen. This antibody exists as a hrp conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-12090A ClonalityPolyclonal
Host SpeciesRabbitTarget NameptsH
Target SynonymsptsH antibody; BSU13900 antibody; Phosphocarrier protein HPr antibody; Histidine-containing protein antibodyFormLiquid
Species ReactivityBacillus subtilisIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateHRP conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Bacillus subtilis Phosphocarrier protein HPr protein (2-88AA)Target SpeciesBacillus subtilis (strain 168)
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP08877
Background Information
  • Uniprot Id

    P08877

  • Target Species

    Bacillus Subtilis

  • Target Name

    PTSH

  • Target Function

    General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The phosphoryl group from phosphoenolpyruvate (PEP) is transferred to the phosphoryl carrier protein HPr by enzyme I. Phospho-HPr then transfers it to the PTS EIIA domain.; P-Ser-HPr interacts with the catabolite control protein A (CcpA), forming a complex that binds to DNA at the catabolite response elements cre, operator sites preceding a large number of catabolite-regulated genes. Thus, P-Ser-HPr is a corepressor in carbon catabolite repression (CCR), a mechanism that allows bacteria to coordinate and optimize the utilization of available carbon sources. P-Ser-HPr also plays a role in inducer exclusion, in which it probably interacts with several non-PTS permeases and inhibits their transport activity.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    HPr family

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