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The antibody against ADAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADAP1 (NP_006860.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against ADAP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADAP1 (NP_006860.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-00091A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADAP1 |
| Target Synonyms | GCS1L; CENTA1; p42IP4; ADAP1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | BT-474, Jurkat, Mouse small intestine, Rat kidney | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-374 of human ADAP1 (NP_006860.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75689 | Immunogen Sequence |
Uniprot Id
O75689
Target Species
Human
Target Name
ADAP1
Target Full Name
Arf-GAP with dual PH domain-containing protein 1
Target Function
GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).
Target Subcellular Location
Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.
Target Tissue Specificity
Expressed at highest levels in brain and at lower levels in peripheral blood leukocytes.
Target Research Area
Microbiology
Target Synonyms
ADAP1; CENTA1Arf-GAP with dual PH domain-containing protein 1; Centaurin-alpha-1; Cnt-a1; Putative MAPK-activating protein PM25
Target Background
Enables GTPase activator activity. Involved in regulation of GTPase activity. Located in cytosol; nucleus; and plasma membrane.
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