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The antibody against ADPRM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ADPRM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03310A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ADPRM |
| Target Synonyms | MDS006; C17orf48; NBLA03831; ADPRM | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse lung, Mouse spleen, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 203-342 of human ADPRM (NP_064618.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | SEPQFVQFNGGFSQEQLNWLNEVLTFSDTNQEKVVIVSHLPIYPDASDNVCLAWNYRDALAVIWSHECVVCFFAGHTHDGGYSEDPFGVYHVNLEGVIETAPDSQAFGTVHVYPDKMMLKGRGRVPDRIMNYKKERAFHC | Uniprot ID | Q3LIE5 |
Uniprot Id
Q3LIE5
Target Species
Human
Target Name
ADPRM
Target Full Name
Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase
Target Function
Hydrolyzes ADP-ribose, IDP-ribose, CDP-glycerol, CDP-choline and CDP-ethanolamine, but not other non-reducing ADP-sugars or CDP-glucose. May be involved in immune cell signaling as suggested by the second-messenger role of ADP-ribose, which activates TRPM2 as a mediator of oxidative/nitrosative stress.
Target Protein Families
ADPRibase-Mn family
Target Synonyms
ADPRM; C17orf48; MDS006; Nbla03831Manganese-dependent ADP-ribose/CDP-alcohol diphosphatase; EC 3.6.1.13; EC 3.6.1.16; EC 3.6.1.53; ADPRibase-Mn; CDP-choline phosphohydrolase
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