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The antibody against AFAP1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against AFAP1L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04745A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AFAP1L2 |
| Target Synonyms | XB130; KIAA1914; CTB-1144G6.4; AFAP1L2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | LO2, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human AFAP1L2 (NP_001001936.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8N4X5 | Immunogen Sequence |
Uniprot Id
Q8N4X5
Target Species
Human
Target Name
AFAP1L2
Target Full Name
Actin filament-associated protein 1-like 2
Target Function
May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.
Target Subcellular Location
Cytoplasm.
Target Tissue Specificity
Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.
Target Synonyms
Actin filament-associated protein 1-like 2; AF1L2_HUMAN; AFAP1-like protein 2; afap1l2; CTB-1144G6.4; KIAA1914; XB130
Target Background
Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane.
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