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Rabbit anti-Human AFAP1L2 Polyclonal Antibody

The antibody against AFAP1L2 was raised in rabbit using the Human AFAP1L2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

ADC-49307A

The antibody against AFAP1L2 was raised in rabbit using the Human AFAP1L2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.

$600.00

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Specifications


Cat.No ADC-49307A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAFAP1L2
Target SynonymsActin filament-associated protein 1-like 2 antibody; AF1L2_HUMAN antibody; AFAP1-like protein 2 antibody; afap1l2 antibody; CTB-1144G6.4 antibody; KIAA1914 antibody; XB130 antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman AFAP1L2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8N4X5
Background Information
  • Uniprot Id

    Q8N4X5

  • Target Species

    Human

  • Target Name

    AFAP1L2

  • Target Full Name

    Actin filament-associated protein 1-like 2

  • Target Function

    May play a role in a signaling cascade by enhancing the kinase activity of SRC. Contributes to SRC-regulated transcription activation.

  • Target Subcellular Location

    Cytoplasm.

  • Target Tissue Specificity

    Detected in spleen and thyroid, and at lower levels in kidney, brain, lung and pancreas.

  • Target Synonyms

    Actin filament-associated protein 1-like 2; AF1L2_HUMAN; AFAP1-like protein 2; afap1l2; CTB-1144G6.4; KIAA1914; XB130

  • Target Background

    Enables SH2 domain binding activity; SH3 domain binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including positive regulation of epidermal growth factor receptor signaling pathway; regulation of gene expression; and regulation of mitotic cell cycle. Located in cytosol and plasma membrane.

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