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The antibody against AGBL2 was raised in rabbit using the Synthesized peptide derived from internal of Human CBCP2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against AGBL2 was raised in rabbit using the Synthesized peptide derived from internal of Human CBCP2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
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Western blot analysis of extracts from HuvEc cells, using CBCP2 antibody.
Immunohistochemistry analysis of paraffin-embedded human heart tissue, using CBCP2 antibody.2
| Cat.No | ADC-41281A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | AGBL2 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CBCP2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q5U5Z8 |
Uniprot Id
Q5U5Z8
Target Species
Human
Target Name
AGBL2
Target Full Name
Cytosolic carboxypeptidase 2
Target Function
Metallocarboxypeptidase that mediates deglutamylation of tubulin and non-tubulin target proteins. Catalyzes the removal of polyglutamate side chains present on the gamma-carboxyl group of glutamate residues within the C-terminal tail of tubulin protein. Specifically cleaves tubulin long-side-chains, while it is not able to remove the branching point glutamate. Also catalyzes the removal of polyglutamate residues from the carboxy-terminus of non-tubulin proteins such as MYLK.
Target Subcellular Location
Cytoplasm, cytosol. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
Peptidase M14 family
Target Synonyms
AGBL 2; AGBL2; ATP/GTP binding protein like 2 ; ATP/GTP-binding protein-like 2; Carboxypeptidase 2 cytosolic; CBPC2_HUMAN; CCP2; Cytosolic carboxypeptidase 2; FLJ23598
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