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The antibody against ALAS2 was raised in rabbit using the Fusion protein of Human ALAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against ALAS2 was raised in rabbit using the Fusion protein of Human ALAS2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-31005A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALAS2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human ALAS2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P22557 |
Uniprot Id
P22557
Target Species
Human
Target Name
ALAS2
Target Full Name
5-aminolevulinate synthase, erythroid-specific, mitochondrial
Target Involvement
Anemia, sideroblastic, 1 (SIDBA1); Erythropoietic protoporphyria, X-linked dominant (XLDPT)
Target Subcellular Location
Mitochondrion matrix.
Target Protein Families
Class-II pyridoxal-phosphate-dependent aminotransferase family
Target Tissue Specificity
Erythroid specific.
Target Research Area
Cancer
Target Synonyms
5 @aminolevulinate synthase erythroid specific; 5 aminolevulinate synthase 2; 5 aminolevulinate synthase 5 aminolevulinate synthase 2; 5 aminolevulinate synthase erythroid specific mitochondrial; 5 aminolevulinic acid synthase 2; 5 aminolevulinic acid synthase; 5-aminolevulinate synthase; 5-aminolevulinic acid synthase 2; Alas 2; ALAS; ALAS E; ALAS; erythroid; ALAS-E; Alas2; ALASE; Aminolevulinate delta synthase 2; Aminolevulinic acid synthase 2; erythroid; ANH1; ASB; Delta ALA synthase 2; Delta ALA synthetase; Delta aminolevulinate synthase 2; Delta aminolevulinate synthase; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2; Erythroid specific ALAS; erythroid-specific; FLJ93603; HEM0_HUMAN; mitochondrial; OTTHUMP00000023388; OTTHUMP00000023389; OTTMUSP00000020679; RP23-338A17.1; SIDBA1; XLDPP; XLEPP; XLSA
Target Background
The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.
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