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Rabbit anti-Human ALDH3B1 Polyclonal Antibody

The antibody against ALDH3B1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ALDH3B1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-39345A

The antibody against ALDH3B1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human ALDH3B1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-39345A ClonalityPolyclonal
Host SpeciesRabbitTarget NameALDH3B1
Target SynonymsALDH3B1 antibody; ALDH7Aldehyde dehydrogenase family 3 member B1 antibody; EC 1.2.1.28 antibody; EC 1.2.1.5 antibody; EC 1.2.1.7 antibody; Aldehyde dehydrogenase 7 antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human ALDH3B1.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP43353
Background Information
  • Uniprot Id

    P43353

  • Target Species

    Human

  • Target Name

    ALDH3B1

  • Target Full Name

    Aldehyde dehydrogenase family 3 member B1

  • Target Function

    Oxidizes medium and long chain saturated and unsaturated aldehydes. Metabolizes also benzaldehyde. Low activity towards acetaldehyde and 3,4-dihydroxyphenylacetaldehyde. May not metabolize short chain aldehydes. Can use both NADP(+) and NAD(+) as electron acceptor. May have a protective role against the cytotoxicity induced by lipid peroxidation.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor. Note=Primarily in the plasma membrane as well as in some punctate structures in the cytoplasm.

  • Target Protein Families

    Aldehyde dehydrogenase family

  • Target Tissue Specificity

    Highest expression in kidney and lung.

  • Target Synonyms

    ALDH3B1; ALDH7Aldehyde dehydrogenase family 3 member B1; EC 1.2.1.28; EC 1.2.1.5; EC 1.2.1.7; Aldehyde dehydrogenase 7

  • Target Background

    This gene encodes a member of the aldehyde dehydrogenase protein family. Aldehyde dehydrogenases are a family of isozymes that may play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The encoded protein is able to oxidize long-chain fatty aldehydes in vitro, and may play a role in protection from oxidative stress. Alternative splicing results in multiple transcript variants.

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