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The antibody against ALMS1 was raised in rabbit using the Recombinant Human Alstrom syndrome protein 1 protein (889-1057AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
The antibody against ALMS1 was raised in rabbit using the Recombinant Human Alstrom syndrome protein 1 protein (889-1057AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IF.
$299.00
| Cat.No | ADC-02003A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ALMS1 |
| Target Synonyms | Alms1 antibody; ALMS1_HUMAN antibody; ALSS antibody; Alstrom syndrome 1 antibody; Alstrom syndrome protein 1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Alstrom syndrome protein 1 protein (889-1057AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TCU4 |
Uniprot Id
Q8TCU4
Target Species
Human
Target Name
ALMS1
Target Full Name
Centrosome-associated protein ALMS1
Target Function
Involved in PCM1-dependent intracellular transport. Required, directly or indirectly, for the localization of NCAPD2 to the proximal ends of centrioles. Required for proper formation and/or maintenance of primary cilia (PC), microtubule-based structures that protrude from the surface of epithelial cells.
Target Involvement
Alstrom syndrome (ALMS)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Associated with centrosomes and basal bodies at the base of primary cilia. Specifically locates to the proximal ends of centrioles and basal bodies. Colocalizes partially with NCAPD2 at these sites. During mitosis localizes to both spindle poles.
Target Tissue Specificity
Expressed in all tissues tested including adipose and pancreas. Expressed by beta-cells of the islets in the pancreas (at protein level).
Target Synonyms
Alms1; ALMS1_HUMAN; ALSS; Alstrom syndrome 1; Alstrom syndrome protein 1
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