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Rabbit anti-Human AMPD3 Polyclonal Antibody

The antibody against AMPD3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AMPD3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

ADC-35598A

The antibody against AMPD3 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human AMPD3. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-35598A ClonalityPolyclonal
Host SpeciesRabbitTarget NameAMPD3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human AMPD3.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ01432
Background Information
  • Uniprot Id

    Q01432

  • Target Species

    Human

  • Target Name

    AMPD3

  • Target Full Name

    AMP deaminase 3

  • Target Function

    AMP deaminase plays a critical role in energy metabolism.

  • Target Involvement

    Adenosine monophosphate deaminase deficiency erythrocyte type (AMPDDE)

  • Target Protein Families

    Metallo-dependent hydrolases superfamily, Adenosine and AMP deaminases family

  • Target Synonyms

    AMPD3

  • Target Background

    This gene encodes a member of the AMP deaminase gene family. The encoded protein is a highly regulated enzyme that catalyzes the hydrolytic deamination of adenosine monophosphate to inosine monophosphate, a branch point in the adenylate catabolic pathway. This gene encodes the erythrocyte (E) isoforms, whereas other family members encode isoforms that predominate in muscle (M) and liver (L) cells. Mutations in this gene lead to the clinically asymptomatic, autosomal recessive condition erythrocyte AMP deaminase deficiency. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

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