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The antibody against ANO2 was raised in rabbit using the Recombinant Human Anoctamin-2 protein (1-83AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ANO2 was raised in rabbit using the Recombinant Human Anoctamin-2 protein (1-83AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
| Cat.No | ADC-06263A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ANO2 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Anoctamin-2 protein (1-83AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NQ90 |
Uniprot Id
Q9NQ90
Target Species
Human
Target Name
ANO2
Target Full Name
Anoctamin-2
Target Function
Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
Anoctamin family
Target Tissue Specificity
Retina, especially in the photoreceptor synaptic terminals.
Target Synonyms
Ano2; ANO2_HUMAN; Anoctamin 2; Anoctamin-2; C12orf3; Chromosome 12 open reading frame 3; DKFZp434P102; Transmembrane protein 16B (eight membrane-spanning domains); Transmembrane protein 16B
Target Background
ANO2 belongs to a family of calcium-activated chloride channels (CaCCs) (reviewed by Hartzell et al., 2009 [PubMed 19015192]).
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