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Rabbit anti-Human BRD3 Polyclonal Antibody

The antibody against BRD3 was raised in rabbit using the Human BRD3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-53976A

The antibody against BRD3 was raised in rabbit using the Human BRD3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-53976A ClonalityPolyclonal
Host SpeciesRabbitTarget NameBRD3
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman BRD3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ15059
Background Information
  • Uniprot Id

    Q15059

  • Target Species

    Human

  • Target Name

    BRD3

  • Target Full Name

    Bromodomain-containing protein 3

  • Target Function

    Chromatin reader that recognizes and binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling and interaction with transcription factors. Regulates transcription by promoting the binding of the transcription factor GATA1 to its targets.

  • Target Involvement

    A chromosomal aberration involving BRD3 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;9)(q14;q34) with NUT which produces a BRD3-NUT fusion protein.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Ubiquitous.

  • Target Synonyms

    BRD 3; Brd3; BRD3_HUMAN; Bromodomain containing 3; Bromodomain containing protein 3; Bromodomain-containing protein 3; KIAA0043 ; Open reading frame X; ORFX; RING3 like gene; RING3-like protein; RING3L

  • Target Background

    This gene was identified based on its homology to the gene encoding the RING3 protein, a serine/threonine kinase. The gene localizes to 9q34, a region which contains several major histocompatibility complex (MHC) genes. The function of the encoded protein is not known.

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