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Rabbit anti-Human CABIN1 Polyclonal Antibody

The antibody against CABIN1 was raised in rabbit using the Recombinant Human Calcineurin-binding protein cabin-1 protein (1978-2123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-03359A

The antibody against CABIN1 was raised in rabbit using the Recombinant Human Calcineurin-binding protein cabin-1 protein (1978-2123AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-03359A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCABIN1
FormLiquidSpecies ReactivityHuman, Rat
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Calcineurin-binding protein cabin-1 protein (1978-2123AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y6J0
Background Information
  • Uniprot Id

    Q9Y6J0

  • Target Species

    Human

  • Target Name

    CABIN1

  • Target Full Name

    Calcineurin-binding protein cabin-1

  • Target Function

    May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it's target genes.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Widely expressed in different tissues.

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