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The antibody against CADM2 was raised in rabbit using the Synthesized peptide derived from internal of Human CADM2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CADM2 was raised in rabbit using the Synthesized peptide derived from internal of Human CADM2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HepG2 cells, using CADM2 antibody.
| Cat.No | ADC-41700A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CADM2 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CADM2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N3J6 |
Uniprot Id
Q8N3J6
Target Species
Human
Target Name
CADM2
Target Full Name
Cell adhesion molecule 2
Target Function
Adhesion molecule that engages in homo- and heterophilic interactions with the other nectin-like family members, leading to cell aggregation. Important for synapse organization, providing regulated trans-synaptic adhesion. Preferentially binds to oligodendrocytes.
Target Subcellular Location
Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Cell projection, axon. Note=Found in the axoplasm of myelinated axons.
Target Protein Families
Nectin family
Target Synonyms
CADM2; CADM2_HUMAN; Cell adhesion molecule 2; IgSF4D; Immunoglobulin superfamily member 4D; NECL 2; Necl 3; NECL-3; NECL2; Necl3; Nectin like protein 3; Nectin-like protein 3; synCAM 2; synCAM2
Target Background
This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
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