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Rabbit anti-Human CCNY Polyclonal Antibody

The antibody against CCNY was raised in rabbit using the Recombinant Human Cyclin-Y protein (2-170AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-05533A

The antibody against CCNY was raised in rabbit using the Recombinant Human Cyclin-Y protein (2-170AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.

$299.00

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Specifications


Cat.No ADC-05533A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCCNY
Target SynonymsCCNY antibody; C10orf9 antibody; CBCP1 antibody; CFP1Cyclin-Y antibody; Cyc-Y antibody; Cyclin box protein 1 antibody; Cyclin fold protein 1 antibody; cyclin-X antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Cyclin-Y protein (2-170AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ8ND76
Background Information
  • Uniprot Id

    Q8ND76

  • Target Species

    Human

  • Target Name

    CCNY

  • Target Full Name

    Cyclin-Y

  • Target Function

    Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.

  • Target Subcellular Location

    Cell membrane; Lipid-anchor; Cytoplasmic side.; [Isoform 3]: Nucleus.

  • Target Protein Families

    Cyclin family, Cyclin Y subfamily

  • Target Tissue Specificity

    Widely expressed.

  • Target Synonyms

    CCNY; C10orf9; CBCP1; CFP1Cyclin-Y; Cyc-Y; Cyclin box protein 1; Cyclin fold protein 1; cyclin-X

  • Target Background

    Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).

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