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The antibody against CEP19 was raised in rabbit using the Recombinant Human Centrosomal protein of 19 kDa protein (1-163AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CEP19 was raised in rabbit using the Recombinant Human Centrosomal protein of 19 kDa protein (1-163AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using CEP19 Antibody at dilution of 1:100
| Cat.No | ADC-10179A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CEP19 |
| Target Synonyms | CEP19 antibody; C3orf34 antibody; HSD5 antibody; Centrosomal protein of 19 kDa antibody; Cep19 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Centrosomal protein of 19 kDa protein (1-163AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96LK0 |
Uniprot Id
Q96LK0
Target Species
Human
Target Name
CEP19
Target Full Name
Centrosomal protein of 19 kDa
Target Function
Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring to the centrosomes.
Target Involvement
Morbid obesity and spermatogenic failure (MOSPGF)
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, spindle pole. Cytoplasm, cytoskeleton, cilium basal body.
Target Protein Families
CEP19 family
Target Synonyms
CEP19; C3orf34; HSD5; Centrosomal protein of 19 kDa; Cep19
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