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Rabbit anti-Human CHD1L Polyclonal Antibody

The antibody against CHD1L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CHD1L. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-37319A

The antibody against CHD1L was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CHD1L. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-37319A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCHD1L
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human CHD1L.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ86WJ1
Background Information
  • Uniprot Id

    Q86WJ1

  • Target Species

    Human

  • Target Name

    CHD1L

  • Target Full Name

    Chromodomain-helicase-DNA-binding protein 1-like

  • Target Function

    DNA helicase which plays a role in chromatin-remodeling following DNA damage. Targeted to sites of DNA damage through interaction with poly(ADP-ribose) and functions to regulate chromatin during DNA repair. Able to catalyze nucleosome sliding in an ATP-dependent manner. Helicase activity is strongly stimulated upon poly(ADP-ribose)-binding.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    SNF2/RAD54 helicase family

  • Target Tissue Specificity

    Frequently overexpressed in hepatomacellular carcinomas.

  • Target Research Area

    Epigenetics and Nuclear Signaling

  • Target Synonyms

    ALC1; Amplified in liver cancer 1; Amplified in liver cancer protein 1; chd1l; CHD1L_HUMAN; CHDL; Chromodomain helicase DNA binding protein 1 like; Chromodomain-helicase-DNA-binding protein 1-like; FLJ22530

  • Target Background

    This gene encodes a DNA helicase protein involved in DNA repair. The protein converts ATP to add poly(ADP-ribose) as it regulates chromatin relaxation following DNA damage. Overexpression of this gene has been linked to several types of cancers.

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