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The antibody against CLDN2 was raised in rabbit using the Recombinant Human Claudin-2 protein (30-230AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against CLDN2 was raised in rabbit using the Recombinant Human Claudin-2 protein (30-230AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human small intestine tissue using CLDN2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human colon cancer using CLDN2 Antibody at dilution of 1:1002
Immunofluorescent analysis of A549 cells using CLDN2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)3
| Cat.No | ADC-45059A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLDN2 |
| Target Synonyms | CLDN2; PSEC0059; SP82; UNQ705/PRO1356; Claudin-2; SP82 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Claudin-2 protein (30-230AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P57739 |
Uniprot Id
P57739
Target Species
Human
Target Name
CLDN2
Target Full Name
Claudin-2
Target Function
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
Target Subcellular Location
Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
Target Protein Families
Claudin family
Target Synonyms
CLDN2; PSEC0059; SP82; UNQ705/PRO1356; Claudin-2; SP82
Target Background
This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.
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