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Rabbit anti-Human COL6A2 Polyclonal Antibody

The antibody against COL6A2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL6A2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

ADC-36374A

The antibody against COL6A2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL6A2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.

$167.00

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Specifications


Cat.No ADC-36374A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCOL6A2
FormLiquidSpecies ReactivityHuman, Mouse, Monkey
IsotypeIgGStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human COL6A2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP12110
Background Information
  • Uniprot Id

    P12110

  • Target Species

    Human

  • Target Name

    COL6A2

  • Target Full Name

    Collagen alpha-2(VI) chain

  • Target Function

    Collagen VI acts as a cell-binding protein.

  • Target Involvement

    Bethlem myopathy 1 (BTHLM1); Ullrich congenital muscular dystrophy 1 (UCMD1); Myosclerosis autosomal recessive (MYOSAR)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix. Membrane; Peripheral membrane protein. Note=Recruited on membranes by CSPG4.

  • Target Protein Families

    Type VI collagen family

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    CO6A2_HUMAN; COL6A2; Collagen alpha 2(VI) chain; Collagen alpha-2(VI) chain; collagen type VI alpha 2; Collagen VI alpha 2 polypeptide; human mRNA for collagen VI alpha 2 C terminal globular domain; PP3610

  • Target Background

    This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.

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