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Rabbit anti-Human CPLX4 Polyclonal Antibody

The antibody against CPLX4 was raised in rabbit using the Recombinant Human Complexin-4 protein (1-157AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

ADC-19523A

The antibody against CPLX4 was raised in rabbit using the Recombinant Human Complexin-4 protein (1-157AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.

$299.00

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Specifications


Cat.No ADC-19523A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCPLX4
Target SynonymsCPLX4Complexin-4 antibody; Complexin IV antibody; CPX IV antibodyFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Complexin-4 protein (1-157AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ7Z7G2
Background Information
  • Uniprot Id

    Q7Z7G2

  • Target Species

    Human

  • Target Name

    CPLX4

  • Target Full Name

    Complexin-4

  • Target Function

    Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release.

  • Target Subcellular Location

    Cell junction, synapse. Cell membrane; Lipid-anchor.

  • Target Protein Families

    Complexin/synaphin family

  • Target Synonyms

    CPLX4Complexin-4; Complexin IV; CPX IV

  • Target Background

    This gene likely encodes a member of the complexin family. The encoded protein may be involved in synaptic vesicle exocytosis.

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