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The antibody against CSDE1 was raised in rabbit using the Recombinant Human Cold shock domain-containing protein E1 protein (433-630AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against CSDE1 was raised in rabbit using the Recombinant Human Cold shock domain-containing protein E1 protein (433-630AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
Immunohistochemistry analysis of human kidney tissue using CSDE1 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using CSDE1 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-12818A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CSDE1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cold shock domain-containing protein E1 protein (433-630AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75534 |
Uniprot Id
O75534
Target Species
Human
Target Name
CSDE1
Target Full Name
Cold shock domain-containing protein E1
Target Function
RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules.; (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA.
Target Subcellular Location
Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS
Target Background
Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex.
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